{"id":5414,"date":"2024-03-12T07:00:00","date_gmt":"2024-03-12T11:00:00","guid":{"rendered":"https:\/\/clariowebstg.wpengine.com\/?post_type=therapeutic-areas&#038;p=5414"},"modified":"2025-07-10T13:50:13","modified_gmt":"2025-07-10T17:50:13","slug":"ophthalmology","status":"publish","type":"therapeutic-areas","link":"https:\/\/clario.com\/therapeutic-areas\/ophthalmology\/","title":{"rendered":"Ophthalmology"},"content":{"rendered":"<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\" id=\"h-ophthalmology-clinical-trials\">Ophthalmology clinical trials<\/h2>\n\n\n\n<p>Clario\u2019s ophthalmology therapeutic area supports clinical trials evaluating the efficacy of therapeutics designed to treat the eye as well as other trial monitoring ophthalmic safety events. Similar to our other therapeutic areas, these services span the entire trial lifecycle of your study, from training and qualification, clinical project and data management, and image QC and analysis to regulatory submission.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section pt-1\">\n  <div class=\"container\">\n      \n<div class=\"row align-items-center\">\n\t\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"544\" height=\"408\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/peter-kaiser-ophthalmology.png\" alt=\"\" class=\"wp-image-5423\"\/><\/figure>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\" id=\"h-the-clario-cleveland-clinic-s-cole-eye-institute-partnership\">The Clario\/Cleveland Clinic\u2019s Cole Eye Institute partnership<\/h2>\n\n\n\n<p>Our collaboration with Drs. Peter K Kaiser, Justis Ehlers, and Sunil Srivistava and their team at The Cole Eye Institute\u2019s Eye Care Center brings the world-class expertise and experience required to provide high-quality endpoint data, enabling you to bring emerging ophthalmic therapies to the market.<\/p>\n\n\n\n<p>Cole has a team of industry-leading ophthalmologists and expert graders that can provide high-quality, fast and reliable ophthalmic image grading. Additionally, the long standing (10+ years) collaboration with Clario includes a generation of AI algorithms that can pre-process and segment images within the clinical trial workflow for a given trial; supplementing the expert graders\u2019 assessments and supporting the generation of new and novel endpoints. Clario brings decades of clinical trial experience and advanced technology with a global footprint and 24\/7 support.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section pt-0\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\" id=\"h-expert-support-throughout-the-trial-lifecycle\">Expert support throughout the trial lifecycle<\/h2>\n\n\n\n<p>When you partner with Clario for your ophthalmology trial, you\u2019ll receive a dedicated, comprehensive approach to all aspects of your study. We pair deep clinical expertise with our broad experience in protocol design, site management and patient support capabilities to provide you with powerful solutions to optimize your study.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n\n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<ul class=\"wp-block-list\">\n<li><strong>Protocol review:<\/strong> Ensure imaging modalities and associated parameters are appropriate and feasible for the proposed study endpoints and provide recommendations on additional exploratory endpoints that may supplement post-approval marketing messaging.<\/li>\n\n\n\n<li><strong>Study design:<\/strong> Design studies to meet your needs both in terms of operational efficiency and regulatory compliance while minimizing patient burden.<\/li>\n\n\n\n<li><strong>Site and equipment\/technologist qualification:<\/strong> Ensure the quality of images generated by equipment and technologists is adequate for assessment of study endpoints with thorough site surveys and a qualification process that includes submission and QC of test imaging prior to the site\u2019s first subject visit.<\/li>\n\n\n\n<li><strong>Site training:<\/strong> Educate site staff on the acquisition parameters and techniques required for a given modality using online training resources and manuals.<\/li>\n\n\n\n<li><strong>Clinical Project Management<\/strong>: Project Management teams excel in delivering results tailored to your study, objectives, timelines, metrics and budgets.<\/li>\n<\/ul>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<ul class=\"wp-block-list\">\n<li><strong>Clinical Data Management: <\/strong>Provide robust data formats and efficient transfer methods that meet industry standards for studies of all complexities.<\/li>\n\n\n\n<li><strong>Quality Review<\/strong>: Check accuracy and completeness of data (image quality, demographics, anatomical coverage and parameter adherence) at each timepoint to ensure images are adequate for assessment.<\/li>\n\n\n\n<li><strong>Image Analysis:<\/strong> Generate highly accurate measurements and turn around assessments quickly if required for eligibility\/safety using a team of specialized graders.<\/li>\n\n\n\n<li><strong>Regulatory submission:<\/strong> Assistance in preparing high-quality data, including exploratory findings, for regulatory submission and presentation.<\/li>\n<\/ul>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section light-grey-50\">\n  <div class=\"container\">\n      \n<div class=\"row mb-3 justify-content-center\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading has-text-align-center\" id=\"validation\">Our Ophthalmology experience and expertise<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n<div class=\"row justify-content-center\">\n\t\n\n<div class=\"col-12 col-md-12\">\n\t\t\t\n<div class=\"clario-statistics-display row justify-content-center\"><div class=\"col-6 col-md-4 col-lg-3 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"Thought Leadership Icon Reverse RGB\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2023\/05\/Thought-Leadership-Icon-Reverse-RGB.svg\" height=\"auto\" width=\"auto\"><p class=\"stat\">20<\/p><p class=\"stat-text\">years&#039; experience<\/p><\/div><div class=\"col-6 col-md-4 col-lg-3 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"World Icon\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2023\/05\/World-Icon-Reverse-RGB.svg\" height=\"auto\" width=\"auto\"><p class=\"stat\">70+<\/p><p class=\"stat-text\">global phase 1-4 trials<\/p><\/div><div class=\"col-6 col-md-4 col-lg-3 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"Customer Experience Icon Reverse RGB\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2023\/05\/Customer-Experience-Icon-Reverse-RGB.svg\" height=\"auto\" width=\"auto\"><p class=\"stat\">4<\/p><p class=\"stat-text\">key opinion leaders<\/p><\/div><div class=\"col-6 col-md-4 col-lg-3 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"Employee Icon Reverse RGB\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2023\/05\/Employee-Icon-Reverse-RGB.svg\" height=\"auto\" width=\"auto\"><p class=\"stat\">20+<\/p><p class=\"stat-text\">expert graders<\/p><\/div><\/div>\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-anchor-navigation sticky-top \">\n  <div class=\"container\">\n    <div class=\"row\">\n      <a href=\"#overview\" class=\"button active nav-link col-auto\">Overview<\/a><a href=\"#capabilities\" class=\"button nav-link col-auto\">Capabilities<\/a><a href=\"#advanced-quantitative-analysis\" class=\"button nav-link col-auto\">Technology<\/a><a href=\"#focus-areas\" class=\"button nav-link col-auto\">Focus areas<\/a>            <button class=\"control arrow closed\" aria-label=\"Toggle\"><\/button>\n    <\/div>\n  <\/div>\n<\/div>\n\n<script type=\"text\/javascript\">\n  jQuery(window).on(\"load\", function() {\n    Clario.AnchorNavigation.run();\n  });\n<\/script>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\" id=\"overview\">Overview<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-clario-s-new-therapeutic-area-combines-20-years-of-ophthalmology-imaging-expertise-with-its-decades-of-cross-therapeutic-area-study-experience\">Clario\u2019s new therapeutic area combines 20 years of ophthalmology imaging expertise, with its decades of cross-therapeutic area study experience.<\/h3>\n\n\n\n<p>The ophthalmology therapeutic area supports a range of ophthalmic <a href=\"https:\/\/clario.com\/solutions\/medical-imaging\/\">imaging modalities<\/a> across all major ophthalmology indications, performing qualitative and quantitative assessments, including advanced, fully customizable proprietary quantitative analysis incorporated within a completely configurable, study-specific workflow. Modalities include OCT\/OCTA, color fundus (CF) photography, fluorescein angiography (FA) and fundus autofluorescence (FAF) across all major ophthalmology indications.<\/p>\n\n\n\n<p>Clario can tailor its ophthalmic software platform to meet study protocol requirements, including, but not limited to, complex workflow design (parallel or interdependent timepoint\/modality workflows), comprehensive QC assessments (supplemented by AI for near real-time quality feedback) and AI-assisted quantitative analysis with customizable per modality grader paradigms (single, 2+1, etc.).&nbsp;<\/p>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section light-grey-50\">\n  <div class=\"container\">\n      \n\n<h2 class=\"wp-block-heading\" id=\"capabilities\">Capabilities<\/h2>\n\n\n\n<p>Clario\u2019s technology accelerates the ophthalmology clinical trial process:<\/p>\n\n\n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<ul class=\"wp-block-list\">\n<li><strong>Real-time access to images: <\/strong>View images\/download images on-demand with or without grader annotations (customizable permission per role, i.e., site, sponsor and medical monitors) at no additional charge.<\/li>\n\n\n\n<li><strong>Intuitive site interface for image upload:<\/strong> Upload images quickly via intuitive drag-and-drop functionality.<\/li>\n\n\n\n<li><strong>Configurable viewers for reader assessments:<\/strong> Vendor agnostic viewer with configurable viewports and annotation\/measurement tools to adjust AI-generated pre-segmented objects (layer lines and fluid, etc.).<\/li>\n\n\n\n<li><strong>Rapid image quality assessment: <\/strong>Near real-time automated quality assessment using AI to notify sites if a rescan is required.<\/li>\n\n\n\n<li><strong>Centralized imaging platform with multi-modal capabilities<\/strong>: Display images from all modalities and for expedited grading and real-time sponsor access. Aggregation of assessments from multiple modalities (e.g., OCT and Fundus) to determine patient eligibility (automated site notifications).<\/li>\n<\/ul>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<ul class=\"wp-block-list\">\n<li><strong>Fully customizable multi-modality workflows and reader paradigms:<\/strong> Incorporate 1\/2\/3 graders and an adjudicator if required, customizable on both a timepoint and modality level.<\/li>\n\n\n\n<li><strong>Advanced proprietary quantitative analysis: <\/strong>Incorporate proprietary quantitative analysis (AI algorithms) into grader assessment workflows to provide consistency and improve efficiency.<\/li>\n\n\n\n<li><strong>21 CFR Part 11 and GDPR compliance:<\/strong> Fully compliant cloud-based platform with verified data integrity checks, access control management, electronic signoffs and a transparent and comprehensive audit trail.<\/li>\n\n\n\n<li><strong>24\/7 global support and deployment: <\/strong>Keep trials on track with 24\/7 global support.<\/li>\n<\/ul>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n\n<h2 class=\"wp-block-heading\" id=\"advanced-quantitative-analysis\">Advanced Quantitative Analysis<\/h2>\n\n\n\n<p>Advanced quantitative analysis is now an essential part of ophthalmology trials.<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<div class=\"wp-block-group d-none\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<h3 class=\"wp-block-heading\" id=\"h-clario-cole-eye-institute-r-amp-d\">Clario\/Cole Eye Institute R&amp;D<\/h3>\n\n\n\n<p>Our R&amp;D arm continually develops quantitative analysis algorithms that enable you to perform advanced assessments and generate quantitative novel endpoints for emerging therapies.<\/p>\n<\/div><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-ai-technology\">AI technology<\/h3>\n\n\n\n<p>Our centralized platform incorporates sophisticated AI technology, which generates segmentations for complex, high-volume assessments that would not be practical or cost-effective for graders to accomplish. These include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>ILM and RPE layer segmentation for retinal thickness analysis<\/li>\n\n\n\n<li>Detection of EZ\/RPE layers for enface ellipsoidal zone disruption mapping<\/li>\n\n\n\n<li>Retinal thickness map analysis for multiple layers (ILM, RPE, Bruchs membrane, ONL, etc.)<\/li>\n\n\n\n<li>Intraretinal\/subretinal fluid and subretinal material segmentation for longitudinal volume change<\/li>\n\n\n\n<li>Evaluation for leakage (perivascular and general), microaneurysm, ischemia and vessel segmentation in fluorescein angiography images<\/li>\n\n\n\n<li>OCT-based GA and c\/iRORA analysis<\/li>\n<\/ul>\n\n\n\n<p>Our AI technology also rapidly assesses OCT\/FA image quality and immediately notifies sites if a rescan is required.<\/p>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"333\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-eyes-image-600x333.png\" alt=\"\" class=\"wp-image-5428\" style=\"width:450px;height:250px\" srcset=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-eyes-image-600x333.png 600w, https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-eyes-image-1200x667.png 1200w, https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-eyes-image-768x427.png 768w, https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-eyes-image-1536x853.png 1536w, https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-eyes-image-2048x1138.png 2048w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"349\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-image-600x349.png\" alt=\"\" class=\"wp-image-5426\" style=\"width:450px;height:262px\" srcset=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-image-600x349.png 600w, https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-image-768x447.png 768w, https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/ophthamology-scan-image.png 820w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure><\/div>\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section light-grey-50\">\n  <div class=\"container\">\n      \n\n<h2 class=\"wp-block-heading\" id=\"focus-areas\">Focus areas<\/h2>\n\n\n    <div class=\"clario-tab-box row  clario-tab-box-col-dark-purple\">\n        <div class=\"nav col-12 col-md-3 flex-column nav-pills\" id=\"clario-tab-box-0ebce61a-controls\" role=\"tablist\" aria-orientation=\"vertical\">\n        <a class=\"nav-link h3 active\" id=\"clario-tab-box-0ebce61a-control-1\" data-toggle=\"pill\" href=\"#clario-tab-box-0ebce61a-content-1\" role=\"tab\" aria-controls=\"clario-tab-box-0ebce61a-content-1\">Supported modalities<\/a>\n<a class=\"nav-link h3\" id=\"clario-tab-box-0ebce61a-control-2\" data-toggle=\"pill\" href=\"#clario-tab-box-0ebce61a-content-2\" role=\"tab\" aria-controls=\"clario-tab-box-0ebce61a-content-2\">Supported indications<\/a>\n<a class=\"nav-link h3\" id=\"clario-tab-box-0ebce61a-control-3\" data-toggle=\"pill\" href=\"#clario-tab-box-0ebce61a-content-3\" role=\"tab\" aria-controls=\"clario-tab-box-0ebce61a-content-3\">Quantitative assessment<\/a>    <\/div>\n    <div class=\"tab-content col-12 col-md-9\" id=\"clario-tab-box-0ebce61a-content\">\n        <div class=\"tab-pane fade show active\" id=\"clario-tab-box-0ebce61a-content-1\" role=\"tabpanel\" aria-labelledby=\"clario-tab-box-0ebce61a-control-1\"><ul>\n<li>OCT\/OCTA (anterior\/posterior, all vendors)<\/li>\n<li>Color fundus photography (CF) (30-60 degrees and wide-field)<\/li>\n<li>Fluorescein angiography (FA) (30-60 degrees and wide-field)<\/li>\n<li>Indocyanine green angiography (ICGA)<\/li>\n<li>Fundus auto-fluorescence (FAF) (30-60 degrees and wide-field)<\/li>\n<li>Infrared reflectance<\/li>\n<li>Slit-lamp photography<\/li>\n<li>Video analysis (e.g., maze\/movement studies)<\/li>\n<\/ul><\/div>\n<div class=\"tab-pane fade\" id=\"clario-tab-box-0ebce61a-content-2\" role=\"tabpanel\" aria-labelledby=\"clario-tab-box-0ebce61a-control-2\"><ul>\n<li>Diabetic retinopathy<\/li>\n<li>Wet\/dry AMD<\/li>\n<li>Uveitis<\/li>\n<li>Retinal vein occlusion<\/li>\n<li>Vitreomacular traction<\/li>\n<li>Epiretinal membrane<\/li>\n<li>Macular hole<\/li>\n<li>Inherited retinal degenerations (e.g., retinitis pigmentosa)<\/li>\n<li>Glaucoma<\/li>\n<li>Optic neuropathies<\/li>\n<li>Neurology (MS studies)<\/li>\n<li>Systemic therapies with ocular side effects<\/li>\n<\/ul><\/div>\n<div class=\"tab-pane fade\" id=\"clario-tab-box-0ebce61a-content-3\" role=\"tabpanel\" aria-labelledby=\"clario-tab-box-0ebce61a-control-3\"><ul>\n<li>OCT layer line segmentation<\/li>\n<li>RPE integrity\/geographic atrophy (OCT\/FA\/FAF\/CF)<\/li>\n<li>CNV location, area, classification (OCT\/OCTA\/FA)<\/li>\n<li>Macular edema, subretinal\/intraretinal fluid, pigment epithelial detachment, drusen analysis, ellipsoidal zone disruption (OCT)<\/li>\n<li>Ischemia, leakage, microaneurysms (FA)<\/li>\n<li>Zonal retinal nerve fiber layer thickness (OCT)<\/li>\n<li>Cup-to-disc ratio (CDR) (CF)<\/li>\n<li>Macular hole volume\/dimensions (OCT)<\/li>\n<li>Diabetic Retinopathy Severity Score (DRSS)<\/li>\n<li>Ischemia, leakage, microaneurysms (FA)<\/li>\n<li>Zonal retinal nerve fiber layer thickness (OCT)<\/li>\n<li>Cup-to-disc ratio (CDR) (CF)<\/li>\n<li>Macular hole volume\/dimensions (OCT)<\/li>\n<li>Diabetic Retinopathy Severity Sc<\/li>\n<\/ul><\/div>    <\/div>\n    <\/div>\n    \n\n    <div class=\"clario-tab-box-mobile row  clario-tab-box-mobile-col-dark-purple\">\n        <div class=\"accordion\" id=\"accordion-69312c300817a\">\n            <div class=\"clario-accordion-title col-12  active nav flex-column nav-pills\" id=\"accordion-heading-0ebce61a\">\n            <a class=\"h3 nav-link  active\" role=\"button\" data-toggle=\"collapse\" data-target=\"#accordion-content-0ebce61a\" aria-expanded=\"false\" aria-controls=\"accordion-content-1\">\n                Supported modalities            <\/a>\n        <\/div>\n        <div class=\"clario-accordion-content nav tab-content collapse col-12  show active\" aria-labelledby=\"accordion-heading-0ebce61a\" id=\"accordion-content-0ebce61a\" data-parent=\"#accordion-69312c300817a\">\n            &lt;ul&gt;\n&lt;li&gt;OCT\/OCTA (anterior\/posterior, all vendors)&lt;\/li&gt;\n&lt;li&gt;Color fundus photography (CF) (30-60 degrees and wide-field)&lt;\/li&gt;\n&lt;li&gt;Fluorescein angiography (FA) (30-60 degrees and wide-field)&lt;\/li&gt;\n&lt;li&gt;Indocyanine green angiography (ICGA)&lt;\/li&gt;\n&lt;li&gt;Fundus auto-fluorescence (FAF) (30-60 degrees and wide-field)&lt;\/li&gt;\n&lt;li&gt;Infrared reflectance&lt;\/li&gt;\n&lt;li&gt;Slit-lamp photography&lt;\/li&gt;\n&lt;li&gt;Video analysis (e.g., maze\/movement studies)&lt;\/li&gt;\n&lt;\/ul&gt;        <\/div>\n                <div class=\"clario-accordion-title col-12  nav flex-column nav-pills\" id=\"accordion-heading-0f2c8624\">\n            <a class=\"h3 nav-link \" role=\"button\" data-toggle=\"collapse\" data-target=\"#accordion-content-0f2c8624\" aria-expanded=\"false\" aria-controls=\"accordion-content-2\">\n                Supported indications            <\/a>\n        <\/div>\n        <div class=\"clario-accordion-content nav tab-content collapse col-12 \" aria-labelledby=\"accordion-heading-0f2c8624\" id=\"accordion-content-0f2c8624\" data-parent=\"#accordion-69312c300817a\">\n            &lt;ul&gt;\n&lt;li&gt;Diabetic retinopathy&lt;\/li&gt;\n&lt;li&gt;Wet\/dry AMD&lt;\/li&gt;\n&lt;li&gt;Uveitis&lt;\/li&gt;\n&lt;li&gt;Retinal vein occlusion&lt;\/li&gt;\n&lt;li&gt;Vitreomacular traction&lt;\/li&gt;\n&lt;li&gt;Epiretinal membrane&lt;\/li&gt;\n&lt;li&gt;Macular hole&lt;\/li&gt;\n&lt;li&gt;Inherited retinal degenerations (e.g., retinitis pigmentosa)&lt;\/li&gt;\n&lt;li&gt;Glaucoma&lt;\/li&gt;\n&lt;li&gt;Optic neuropathies&lt;\/li&gt;\n&lt;li&gt;Neurology (MS studies)&lt;\/li&gt;\n&lt;li&gt;Systemic therapies with ocular side effects&lt;\/li&gt;\n&lt;\/ul&gt;        <\/div>\n                <div class=\"clario-accordion-title col-12  nav flex-column nav-pills\" id=\"accordion-heading-b08eb14b\">\n            <a class=\"h3 nav-link \" role=\"button\" data-toggle=\"collapse\" data-target=\"#accordion-content-b08eb14b\" aria-expanded=\"false\" aria-controls=\"accordion-content-3\">\n                Quantitative assessment            <\/a>\n        <\/div>\n        <div class=\"clario-accordion-content nav tab-content collapse col-12 \" aria-labelledby=\"accordion-heading-b08eb14b\" id=\"accordion-content-b08eb14b\" data-parent=\"#accordion-69312c300817a\">\n            &lt;ul&gt;\n&lt;li&gt;OCT layer line segmentation&lt;\/li&gt;\n&lt;li&gt;RPE integrity\/geographic atrophy (OCT\/FA\/FAF\/CF)&lt;\/li&gt;\n&lt;li&gt;CNV location, area, classification (OCT\/OCTA\/FA)&lt;\/li&gt;\n&lt;li&gt;Macular edema, subretinal\/intraretinal fluid, pigment epithelial detachment, drusen analysis, ellipsoidal zone disruption (OCT)&lt;\/li&gt;\n&lt;li&gt;Ischemia, leakage, microaneurysms (FA)&lt;\/li&gt;\n&lt;li&gt;Zonal retinal nerve fiber layer thickness (OCT)&lt;\/li&gt;\n&lt;li&gt;Cup-to-disc ratio (CDR) (CF)&lt;\/li&gt;\n&lt;li&gt;Macular hole volume\/dimensions (OCT)&lt;\/li&gt;\n&lt;li&gt;Diabetic Retinopathy Severity Score (DRSS)&lt;\/li&gt;\n&lt;li&gt;Ischemia, leakage, microaneurysms (FA)&lt;\/li&gt;\n&lt;li&gt;Zonal retinal nerve fiber layer thickness (OCT)&lt;\/li&gt;\n&lt;li&gt;Cup-to-disc ratio (CDR) (CF)&lt;\/li&gt;\n&lt;li&gt;Macular hole volume\/dimensions (OCT)&lt;\/li&gt;\n&lt;li&gt;Diabetic Retinopathy Severity Sc&lt;\/li&gt;\n&lt;\/ul&gt;        <\/div>\n                <\/div>\n    <\/div>\n    \n<script type=\"text\/javascript\">\nif (jQuery(window).width() <= 768) {\n    Clario.$(\".clario-tab-box-mobile .clario-accordion-title .nav-link\").click(function () {\n        var clickedCard = Clario.$(this);\n        \n        setTimeout(function() {\n            if (clickedCard.attr(\"aria-expanded\") === \"true\") {\n                isOpen = \"true\";\n            } else {\n                isOpen = \"false\";\n            }\n\n            if (isOpen == \"true\") {\n                clickedCard.addClass(\"active\");\n            } else {\n                clickedCard.removeClass(\"active\");\n            }\n        }, 200);\n    });\n}\n<\/script>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n\n<h2 class=\"wp-block-heading\" id=\"h-key-benefits-to-sponsors\">Key benefits to sponsors<\/h2>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-4\">\n\t\t\t\n<div class=\"wp-block-image animate__fadeInUp animation-delay-1\">\n<figure class=\"aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/Drug-Approval-Icon-RGB.svg\" alt=\"\" class=\"wp-image-5436\" style=\"width:75px;height:75px\"\/><\/figure><\/div>\n\n\n<p class=\"has-text-align-center\">Bring emerging therapies to market<\/p>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-4\">\n\t\t\t\n<div class=\"wp-block-image animate__fadeInUp animation-delay-2\">\n<figure class=\"aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/01\/Regulatory-Approval-Icon.svg\" alt=\"Regulatory Approval Icon\" class=\"wp-image-3377\" style=\"width:75px;height:75px\"\/><\/figure><\/div>\n\n\n<p class=\"has-text-align-center\">Enhance regulatory submissions<\/p>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-4\">\n\t\t\t\n<div class=\"wp-block-image animate__fadeInUp animation-delay-3\">\n<figure class=\"aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/01\/Patient-Recruitment-Icon.svg\" alt=\"Patient Recruitment Icon\" class=\"wp-image-3376\" style=\"width:75px;height:75px\"\/><\/figure><\/div>\n\n\n<p class=\"has-text-align-center\">Improve clinical trial experience<\/p>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section clario-cta clario-cta-layout-standard  purple show-bg-pixel \">\n  <div class=\"container\">\n    <div class=\"row align-items-md-center\">\n        <div class=\"clario-cta-content col-md-6 offset-md-1 col-10\"><p class=\"h2\">Talk to a specialist to get started<\/p><p><p>Our team of experts are available to address any questions you may have about our ophthalmology solutions. Submit your contact information and we\u2019ll be in touch shortly.<\/p>\n<\/p><\/div><div class=\"cta-buttons offset-md-1 col-md-4 col-10\"><div class=\"clario-cta-action\"><a href=\"#popup-1\" class=\"button cta-1 \">Get started<\/a><\/div><\/div>    <\/div>\n  <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Advance ophthalmic therapeutic from study start-up to regulatory submission with proven site support, project management, and medical expertise. [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/clario.com\/therapeutic-areas\/ophthalmology\/\">Read More&#8230;<span class=\"screen-reader-text\"> from Ophthalmology<\/span><\/a><\/p>\n","protected":false},"featured_media":5800,"parent":0,"menu_order":0,"template":"","tags":[136,280,131,142,149,151,164,281],"class_list":["post-5414","therapeutic-areas","type-therapeutic-areas","status-publish","has-post-thumbnail","hentry","tag-cardiac-safety","tag-corporate-marketing","tag-ecoa","tag-medical-imaging","tag-precision-motion","tag-respiratory","tag-software-solutions","tag-specialty-solutions"],"acf":[],"cp_meta_data":{"_edit_lock":["1752173037:7"],"_edit_last":["7"],"page_title":[""],"_page_title":["field_615dbd9cfca50"],"banner_image":["5800"],"_banner_image":["field_614c580034347"],"show_header_pixel":["1"],"_show_header_pixel":["field_6221d6b147ede"],"introduction":["Advance ophthalmic therapeutic from study start-up to regulatory 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