{"id":3753,"date":"2022-04-28T05:23:57","date_gmt":"2022-04-28T09:23:57","guid":{"rendered":"https:\/\/clariowebstg.wpengine.com\/?post_type=therapeutic-areas&#038;p=3753"},"modified":"2025-09-16T08:40:27","modified_gmt":"2025-09-16T12:40:27","slug":"hepatology","status":"publish","type":"therapeutic-areas","link":"https:\/\/clario.com\/therapeutic-areas\/hepatology\/","title":{"rendered":"Hepatology"},"content":{"rendered":"<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row mb-3\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading h3\" id=\"h-state-of-the-art-nafld-nash-assessment\">State-of-the-art NAFLD\/NASH assessment<\/h2>\n\n\n\n<p>Clario\u2019s therapeutic expertise and our <a href=\"https:\/\/clario.com\/solutions\/medical-imaging\/general-medicine\/\">best-in-class image analysis and systems<\/a> provide you with comprehensive Non-Alcoholic Fatty Liver Disease (NAFLD)\/Non-Alcoholic Steatohepatitis (NASH) clinical trial management and study support \u2014 from start to finish.<\/p>\n\n\n\n<p>When combined with clinical data, our non-invasive imaging techniques expedite the assessment of disease severity and provide you with a more accurate picture of disease changes. Through our understanding of the complexities of NAFLD\/NASH endpoints, our liver clinical trial management experts can help you customize a biomarker and imaging package specific to your trial\u2019s goals and objectives.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n\n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading h3\">Changing the way liver disease is monitored<\/h2>\n\n\n\n<p>Surgical biopsy, the current diagnostic standard, is invasive, expensive, and painful. Biopsies also only provide information from just a small part of the liver, so relying on biopsies alone can often delay diagnosis and treatment \u2014 often until cirrhosis or liver cancer is present. At Clario, our liver clinical trial team utilizes advanced medical imaging to provide important, quantitative information on liver changes in NAFLD\/NASH patients \u2014 useful data to help inform patient eligibility and to determine drug efficacy.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section light-grey-50\">\n  <div class=\"container\">\n      \n<div class=\"row mb-3 justify-content-center\">\n\t\n\n<div class=\"col-12 col-md-12\">\n\t\t\t\n\n<h2 class=\"wp-block-heading has-text-align-center h3\">Hepatology experience<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-12\">\n\t\t\t\n<div class=\"clario-statistics-display row justify-content-center\"><div class=\"col-6 col-md-4 col-lg-4 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"\" src=\"\" height=\"auto\" width=\"auto\"><p class=\"stat\">55+<\/p><p class=\"stat-text\">Liver\/Muscle Dixon studies<\/p><\/div><div class=\"col-6 col-md-4 col-lg-4 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"\" src=\"\" height=\"auto\" width=\"auto\"><p class=\"stat\">20+<\/p><p class=\"stat-text\">Liver studies with MRI-PDFF, MR Elastography and SAT\/VAT depot analysis<\/p><\/div><div class=\"col-6 col-md-4 col-lg-4 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"\" src=\"\" height=\"auto\" width=\"auto\"><p class=\"stat\">320+<\/p><p class=\"stat-text\">Study sites<\/p><\/div><div class=\"col-6 col-md-4 col-lg-4 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"\" src=\"\" height=\"auto\" width=\"auto\"><p class=\"stat\">2,225+<\/p><p class=\"stat-text\">Magnetic resonance imaging. Proton density fat fraction (MRI-PDFF) analyses<\/p><\/div><div class=\"col-6 col-md-4 col-lg-4 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"\" src=\"\" height=\"auto\" width=\"auto\"><p class=\"stat\">750+<\/p><p class=\"stat-text\">MR elastography (MRE) analyses<\/p><\/div><div class=\"col-6 col-md-4 col-lg-4 stat-block\"><img decoding=\"async\" class=\"stat-block-icons\" alt=\"\" src=\"\" height=\"auto\" width=\"auto\"><p class=\"stat\">600+<\/p><p class=\"stat-text\">SAT\/VAT segmentation<\/p><\/div><\/div>\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading h3\">Improving enrollment and retention with timely image reads that are right the first time<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Accurate, consistent, reliable measurements through independent, software-assisted review of liver images and quantitative analysis<\/li>\n\n\n\n<li>Data quality ensured by expert radiologist review of every measurement and our reader monitoring program<\/li>\n\n\n\n<li>Trial status updates are easy with real-time access to eligibility and safety reports<\/li>\n\n\n\n<li>A wide range of image formats supports transfer\/archiving to external vendors and partners<\/li>\n<\/ul>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-anchor-navigation sticky-top \">\n  <div class=\"container\">\n    <div class=\"row\">\n      <a href=\"#overview\" class=\"button active nav-link col-auto\">Overview<\/a><a href=\"#capabilities\" class=\"button nav-link col-auto\">Capabilities<\/a><a href=\"#focus-areas\" class=\"button nav-link col-auto\">Focus areas<\/a>            <button class=\"control arrow closed\" aria-label=\"Toggle\"><\/button>\n    <\/div>\n  <\/div>\n<\/div>\n\n<script type=\"text\/javascript\">\n  jQuery(window).on(\"load\", function() {\n    Clario.AnchorNavigation.run();\n  });\n<\/script>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\" id=\"overview\">Overview<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Leverage our therapeutic expertise in liver clinical trial management and nephrology studies, our regulatory leadership and our global operations to design and expedite your NAFLD\/NASH clinical trials, from protocol development to regulatory submission.<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">Expertise<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Guidance to identify the optimal modalities for screening specific to your study\u2019s needs<\/li>\n\n\n\n<li>Determination of trial-specific liver endpoints<\/li>\n\n\n\n<li>Measurement of liver fat and stiffness as well as subcutaneous and visceral adipose tissue compartments<\/li>\n\n\n\n<li>Development of imaging protocols and imaging charter<\/li>\n\n\n\n<li>Design of independent review methodology<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Services<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Robust site setup and qualification of imaging personnel and equipment during the liver clinical trial management process<\/li>\n\n\n\n<li>Comprehensive training on image acquisition<\/li>\n\n\n\n<li>Extensive quality review of incoming data<\/li>\n\n\n\n<li>Precise measurement of liver fat fraction (proton density fat fraction) and liver stiffness (MR elastography)<\/li>\n\n\n\n<li>Rapid eligibility analysis by global internal readers<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Experience<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pairing the right biomarker and liver measurements with the specific trial goals<\/li>\n\n\n\n<li>Facilitating patient enrollment through timely image reads<\/li>\n\n\n\n<li>Retaining patients by minimizing the need for repeat scans<\/li>\n<\/ul>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section light-grey-50\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\" id=\"capabilities\">Capabilities<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Our experience covers the complete range of imaging modalities for hepatology research, including:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Magnetic Resonance Imaging \u2013 Proton Density Fat Fraction (MRI-PDFF)<\/li>\n\n\n\n<li>Magnetic Resonance Elastography (MRE)<\/li>\n<\/ul>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\" id=\"focus-areas\">Focus areas<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Our experience includes imaging support for the following indications and areas:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Non-Alcoholic Fatty Liver Disease (NAFLD)<\/li>\n\n\n\n<li>Non-Alcoholic Steatohepatitis (NASH)<\/li>\n\n\n\n<li>Compensated\/Decompensated Cirrhotic liver stiffness<\/li>\n\n\n\n<li>Varices in NASH<\/li>\n<\/ul>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section clario-cta clario-cta-layout-standard  purple show-bg-pixel \">\n  <div class=\"container\">\n    <div class=\"row align-items-md-center\">\n        <div class=\"clario-cta-content col-md-6 offset-md-1 col-10\"><p class=\"h2\">Talk to a specialist to get started<\/p><p><p>Our team of experts is available to address any questions you may have about our hepatology solutions. Submit your contact information and we\u2019ll be in touch shortly.<\/p>\n<\/p><\/div><div class=\"cta-buttons offset-md-1 col-md-4 col-10\"><div class=\"clario-cta-action\"><a href=\"#popup-1\" class=\"button cta-1 \">Get started<\/a><\/div><\/div>    <\/div>\n  <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Accelerating liver status assessments through advanced non-invasive medical imaging [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/clario.com\/therapeutic-areas\/hepatology\/\">Read More&#8230;<span class=\"screen-reader-text\"> from Hepatology<\/span><\/a><\/p>\n","protected":false},"featured_media":0,"parent":0,"menu_order":5,"template":"","tags":[136,280,131,142,149,151,164,281],"class_list":["post-3753","therapeutic-areas","type-therapeutic-areas","status-publish","hentry","tag-cardiac-safety","tag-corporate-marketing","tag-ecoa","tag-medical-imaging","tag-precision-motion","tag-respiratory","tag-software-solutions","tag-specialty-solutions"],"acf":[],"cp_meta_data":{"_wp_old_date":["2022-04-27"],"_edit_last":["29"],"page_title":[""],"_page_title":["field_615dbd9cfca50"],"banner_image":["8013"],"_banner_image":["field_614c580034347"],"show_header_pixel":["1"],"_show_header_pixel":["field_6221d6b147ede"],"introduction":["Accelerate your liver status assessments through advanced non-invasive medical 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