{"id":13220,"date":"2025-07-31T13:56:12","date_gmt":"2025-07-31T17:56:12","guid":{"rendered":"https:\/\/clario.com\/?post_type=therapeutic-areas&#038;p=13220"},"modified":"2025-07-31T14:40:50","modified_gmt":"2025-07-31T18:40:50","slug":"dementias","status":"publish","type":"therapeutic-areas","link":"https:\/\/clario.com\/therapeutic-areas\/neuroscience\/dementias\/","title":{"rendered":"Dementias"},"content":{"rendered":"<div class=\"clario-anchor-navigation sticky-top \">\n  <div class=\"container\">\n    <div class=\"row\">\n      <a href=\"#overview\" class=\"button active nav-link col-auto\">Overview<\/a><a href=\"#solutions-and-expertise\" class=\"button nav-link col-auto\">Solutions and expertise<\/a>            <button class=\"control arrow closed\" aria-label=\"Toggle\"><\/button>\n    <\/div>\n  <\/div>\n<\/div>\n\n<script type=\"text\/javascript\">\n  jQuery(window).on(\"load\", function() {\n    Clario.AnchorNavigation.run();\n  });\n<\/script>\n\n\n<div class=\"clario-section light-grey-50\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<p class=\"mb-0 has-pattern-4-color has-text-color\" id=\"overview\" style=\"font-style:normal;font-weight:600\">OVERVIEW<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-turn-complexity-into-clarity\">Turn complexity into clarity<\/h2>\n\n\n\n<p>Dementia trials are complex, but they don\u2019t have to be difficult. Clario combines proven technology with scientific expertise to help you generate high-quality data, reduce variability, and stay aligned with regulatory requirements &#8211; every step of the way.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section pb-0 mb-0\">\n  <div class=\"container\">\n      \n<div class=\"row\">\n\t\n\n<div class=\"col-12 col-md-9\">\n\t\t\t\n\n<p class=\"mb-0 has-pattern-4-color has-text-color\" id=\"solutions-and-expertise\" style=\"font-style:normal;font-weight:600\">SOLUTIONS AND EXPERTISE<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-empower-your-dementia-trials-with-accurate-actionable-data\">Empower your dementia trials with accurate, actionable data<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row align-items-center\">\n\t\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n<div class=\"responsive-image-block\">\n    <div class=\"row justify-content-between align-items-center\">\n        <div class=\"col-12 mb-2 responsive-image\">\n            <div class=\"img-container img-container-desktop\">\n                                    <img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2021\/12\/fleximaging-image-2-1.png\" class=\"default-pixel img-fluid\" height=\"auto\" width=\"auto\" alt=\"Man getting an MRI scan in hospital\">\n                            <\/div>\n            <div class=\"img-container img-container-mobile\">\n                                    <img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2021\/12\/fleximaging-image-2-1.png\" class=\"default-pixel img-fluid\" height=\"auto\" width=\"auto\" alt=\"Man getting an MRI scan in hospital\">\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<h3 class=\"wp-block-heading\" id=\"h-reveal-deeper-insights-with-advanced-imaging\"><strong>Reveal deeper insights<\/strong> with advanced imaging<\/h3>\n\n\n\n<p>Neuroimaging is essential for tracking disease progression and treatment effect. Clario&#8217;s advanced MRI, CT, FDG-PET, and molecular imaging solutions provide precise, quantitative data to confirm eligibility, monitor change, and validate endpoints.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Detect<\/strong> early structural and functional brain changes<\/li>\n\n\n\n<li><strong>Visualize<\/strong> Tau and beta-amyloid with molecular imaging<\/li>\n\n\n\n<li><strong>Standardize<\/strong> acquisition for consistent, reliable data<\/li>\n\n\n\n<li><strong>Access<\/strong> expert reads aligned with regulatory criteria<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-buttons mt-2 is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-secondary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/clario.com\/solutions\/medical-imaging\/\">Explore advanced imaging solutions<\/a><\/div>\n<\/div>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row align-items-center\">\n\t\n\n<div class=\"col-12 col-md-6 order-md-2\">\n\t\t\t\n<div class=\"responsive-image-block\">\n    <div class=\"row justify-content-between align-items-center\">\n        <div class=\"col-12 mb-2 responsive-image\">\n            <div class=\"img-container img-container-desktop\">\n                                    <img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2025\/06\/phase-1-rapid-start.png\" class=\"default-pixel img-fluid\" height=\"auto\" width=\"auto\" alt=\"\">\n                            <\/div>\n            <div class=\"img-container img-container-mobile\">\n                                    <img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2025\/06\/phase-1-rapid-start.png\" class=\"default-pixel img-fluid\" height=\"auto\" width=\"auto\" alt=\"\">\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<h3 class=\"wp-block-heading\" id=\"h-capture-cognitive-changes-with-smarter-ecoa\"><strong>Capture cognitive changes<\/strong> with smarter eCOA<\/h3>\n\n\n\n<p>Cognitive assessments are central to dementia trials &#8211; and precision is non-negotiable. Clario&#8217;s neuroscience-optimized eCOA platform ensures accuracy at every step, from rater training to data review.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Deliver<\/strong> complex cognitive assessments with multimedia tools<\/li>\n\n\n\n<li><strong>Equip<\/strong> raters with advanced, neuroscience-focused training<\/li>\n\n\n\n<li><strong>Monitor<\/strong> in real time to detect and correct data quality issues<\/li>\n\n\n\n<li><strong>Improve<\/strong> retention with eConsent and Patient Connect<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-buttons mt-2 is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-secondary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/clario.com\/solutions\/ecoa\/\">Learn more about our eCOA solutions<\/a><\/div>\n<\/div>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row align-items-center\">\n\t\n\n<div class=\"col-12 col-md-6 mb-3 mb-md-0\">\n\t\t\t\n\n<div class=\"clario-video-lightbox \">\n    <button class=\"no-button wp-embed-aspect-16-9 wp-has-aspect-ratio\" data-toggle=\"modal\" data-target=\"#video-lightbox-3d3ef226\" tabindex=\"0\" aria-label=\"Watch video\">\n        <img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"449\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2025\/07\/Advancing-Alzheimers-Clinical-Trial-Endpoints-thumbnail-800x449.png\" class=\"img-fluid\" alt=\"Advancing Alzheimer\u2019s Clinical Trial Endpoints thumbnail\" \/>    <\/button>\n<\/div>\n\n<div class=\"clario-video-lightbox-modal modal no-frame fade\" id=\"video-lightbox-3d3ef226\" tabindex=\"-1\" role=\"dialog\" aria-hidden=\"true\">\n    <div class=\"modal-dialog modal-dialog-centered modal-xl\" role=\"document\">\n        <div class=\"modal-content\">\n            <div class=\"modal-body\">\n                <div class=\"video-player\" itemprop=\"video\" itemscope itemtype=\"http:\/\/schema.org\/VideoObject\"><iframe loading=\"lazy\" title=\"Advancing Alzheimer\u2019s Clinical Trial Endpoints\" width=\"640\" height=\"360\" src=\"https:\/\/www.youtube.com\/embed\/A4f-lxkyP4A?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><meta itemprop=\"name\" content=\"Video\" \/><meta itemprop=\"description\" content=\"Event video\" \/><meta itemprop=\"thumbnailUrl\" content=\"https:\/\/clario.com\/wp-content\/themes\/understrap\/assets\/default-thumb.jpg\" \/><meta itemprop=\"uploadDate\" content=\"2025-12-04T06:34:06+00:00\" \/><meta itemprop=\"embedUrl\" content=\"https:\/\/youtu.be\/A4f-lxkyP4A?si=d0Pf9_qDfzt4sHQu\" \/><\/div>            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<script type=\"text\/javascript\">\n    jQuery(window).on(\"load\", function() {\n        Clario.VideoLightbox.configure('#video-lightbox-3d3ef226', false); \/\/ Escape JS output\n    });\n<\/script>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<h3 class=\"wp-block-heading\" id=\"h-track-subtle-motor-changes-with-wearable-technology\"><strong>Track subtle motor changes<\/strong> with wearable technology<\/h3>\n\n\n\n<p>Motor dysfunction often precedes cognitive symptoms in dementia. Clario\u2019s Opal wearable sensors deliver objective, highly-sensitive data on gait and balance &#8211; capturing early signs of decline and enhancing your endpoint strategy.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Detect<\/strong> early gait and balance impairments<\/li>\n\n\n\n<li><strong>Collect<\/strong> real-world, continuous movement data<\/li>\n\n\n\n<li><strong>Strengthen<\/strong> clinical outcome measures with objective insights<\/li>\n<\/ul>\n\n\n\n<p>Watch our webinar on wearable sensor data.<\/p>\n\n\n\n<div class=\"wp-block-buttons mt-2 is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-secondary\" data-target=\"#video-lightbox-3d3ef226\" data-toggle=\"modal\"><a class=\"wp-block-button__link wp-element-button\">Watch webinar<\/a><\/div>\n<\/div>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row align-items-center\">\n\t\n\n<div class=\"col-12 col-md-6 order-md-2\">\n\t\t\t\n<div class=\"responsive-image-block\">\n    <div class=\"row justify-content-between align-items-center\">\n        <div class=\"col-12 mb-2 responsive-image\">\n            <div class=\"img-container img-container-desktop\">\n                                    <img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/03\/RS-we-scale-globally.png\" class=\"default-pixel img-fluid\" height=\"auto\" width=\"auto\" alt=\"Woman on a video call with a medical professional\">\n                            <\/div>\n            <div class=\"img-container img-container-mobile\">\n                                    <img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/03\/RS-we-scale-globally.png\" class=\"default-pixel img-fluid\" height=\"auto\" width=\"auto\" alt=\"Woman on a video call with a medical professional\">\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<h3 class=\"wp-block-heading\" id=\"h-protect-patient-safety-with-integrated-cardiac-and-respiratory-monitoring\"><strong>Protect patient safety<\/strong> with integrated cardiac and respiratory monitoring<\/h3>\n\n\n\n<p>Older adults with dementia are at higher risk for cardiac and respiratory complications. Clario&#8217;s targeted safety solutions help you identify risks early and maintain compliance without slowing down your study.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Monitor<\/strong> cardiovascular safety with intensive QT and BP assessments<\/li>\n\n\n\n<li><strong>Capture<\/strong> high-quality spirometry and pulmonary function data<\/li>\n\n\n\n<li><strong>Centralize<\/strong> safety oversight seamlessly across your study<\/li>\n<\/ul>\n\n\n\n<p>Learn more about our cardiac and respiratory solutions.<\/p>\n\n\n\n<div class=\"wp-block-buttons mt-2 is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-secondary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/clario.com\/solutions\/cardiac-solutions\/\">Cardiac solutions<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-secondary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/clario.com\/solutions\/respiratory\/\">Respiratory solutions<\/a><\/div>\n<\/div>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section\">\n  <div class=\"container\">\n      \n<div class=\"row align-items-center\">\n\t\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n<div class=\"responsive-image-block\">\n    <div class=\"row justify-content-between align-items-center\">\n        <div class=\"col-12 mb-2 responsive-image\">\n            <div class=\"img-container img-container-desktop\">\n                                    <img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/5-reasons-listicle-pixel-image.png\" class=\"default-pixel img-fluid\" height=\"auto\" width=\"auto\" alt=\"5-reasons-listicle-pixel-image\">\n                            <\/div>\n            <div class=\"img-container img-container-mobile\">\n                                    <img decoding=\"async\" src=\"https:\/\/clario.com\/wp-content\/uploads\/2022\/06\/5-reasons-listicle-pixel-image.png\" class=\"default-pixel img-fluid\" height=\"auto\" width=\"auto\" alt=\"5-reasons-listicle-pixel-image\">\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-6\">\n\t\t\t\n\n<h3 class=\"wp-block-heading\" id=\"h-strengthen-decisions-with-expert-adjudication\"><strong>Strengthen decisions<\/strong> with expert adjudication<\/h3>\n\n\n\n<p>In dementia trials, neuro-related events require precise evaluation to ensure consistent reporting. Clario\u2019s Clinical Event Committee ensures accurate, defensible data to bolster your regulatory confidence.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Centralize<\/strong> neuro-related event review with independent experts<\/li>\n\n\n\n<li><strong>Standardized<\/strong> criteria for clear, defensible classifications<\/li>\n\n\n\n<li><strong>Streamline<\/strong> regulatory submissions with high-quality data<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-buttons mt-2 is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-secondary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/clario.com\/solutions\/trial-enablement\/clinical-adjudication\/\" target=\"_blank\" rel=\"noreferrer noopener\">Explore our clinical adjudication services<\/a><\/div>\n<\/div>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n\n\n<div class=\"clario-section light-grey-50 pt-0 pb-1\">\n  <div class=\"container\">\n      \n<div class=\"row my-3 justify-content-center\">\n\t\n\n<div class=\"col-12 col-md-10 pt-3\">\n\t\t\t\n\n<h2 class=\"wp-block-heading has-text-align-center\" id=\"h-move-forward-with-confidence\">Move forward with confidence<\/h2>\n\n\n\n<p class=\"has-text-align-center\">Clario simplifies the complexity of dementia trials so you can focus on outcomes. With unmatched neuroscience expertise, integrated technologies, and a relentless focus on quality, we help you make better decisions, faster.<\/p>\n\n\n\n<h3 class=\"wp-block-heading has-text-align-center\" id=\"h-let-s-turn-complexity-into-confident-action\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-pink-color\">Let&#8217;s turn complexity into confident action.<\/mark><\/h3>\n\n\n\n<div class=\"wp-block-buttons btn-sm-center is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-secondary is-style-cta-1\"><a class=\"wp-block-button__link wp-element-button\" href=\"#popup-1\">Start simplifying your complexity<\/a><\/div>\n<\/div>\n\n\t<\/div>\n\n<\/div>\n\n  <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p> [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/clario.com\/therapeutic-areas\/neuroscience\/dementias\/\">Read More&#8230;<span class=\"screen-reader-text\"> from Dementias<\/span><\/a><\/p>\n","protected":false},"featured_media":13226,"parent":5024,"menu_order":0,"template":"","tags":[],"class_list":["post-13220","therapeutic-areas","type-therapeutic-areas","status-publish","has-post-thumbnail","hentry"],"acf":[],"cp_meta_data":{"bt_post_experiments_editor":["gutenberg"],"page_title":[""],"_page_title":["field_615dbd9cfca50"],"select_hero_section_type":["image"],"_select_hero_section_type":["field_63e9c1ac237af"],"banner_image":["13226"],"_banner_image":["field_614c580034347"],"show_header_pixel":["1"],"_show_header_pixel":["field_6221d6b147ede"],"introduction":["<strong>Dementias, including Alzheimer\u2019s disease affect millions worldwide<\/strong> and remain a major unmet need. Advancing treatment depends on accurate, reliable data in a field with complex, evolving endpoints."],"_introduction":["field_614c581e34348"],"introduction_paragraph":["<em>\"Clario\u2019s neuroscience experts have supported 700+ Alzheimer\u2019s studies, providing reliable assessment of eligibility, safety, and efficacy. We help sponsors select optimal endpoints, enhance data quality, and scale globally. Through imaging, eCOA, wearables, and safety monitoring, we deliver the insights needed to help accelerate drug development.\"  <\/em> <br><br>David Scott, Ph.D.<br>Vice President, Medical and Scientific Affairs at Clario"],"_introduction_paragraph":["field_629ee2f209b6b"],"call_to_action_button":["1"],"_call_to_action_button":["field_629888a6435a9"],"cta_btn_css_class":[""],"_cta_btn_css_class":["field_62bab8d5adfa4"],"display_prefooter":["hide"],"_display_prefooter":["field_61641783f0f7c"],"persistent_cta":["hide"],"_persistent_cta":["field_6375dc7c0b25c"],"show_popup":["1"],"_show_popup":["field_62b1aec56dcb5"],"solutions":[""],"_solutions":["field_61eac16edee33"],"solutions_category":[""],"_solutions_category":["field_61eac09d5e59c"],"therapeutic_area_icon":[""],"_therapeutic_area_icon":["field_62445225df5f2"],"therapeutic_areas":[""],"_therapeutic_areas":["field_61eac19284449"],"_yoast_wpseo_content_score":["30"],"_yoast_wpseo_focuskeywords":[""],"_yoast_wpseo_keywordsynonyms":[""],"_yoast_wpseo_estimated-reading-time-minutes":["3"],"cta_btn_text":["Get started"],"_cta_btn_text":["field_62984e409758b"],"cta_btn_url":["#popup-1"],"_cta_btn_url":["field_62984e699758c"],"cta_url_open_new_tab":["0"],"_cta_url_open_new_tab":["field_629dce361d7e6"],"cta_btn_style":["cta-1"],"_cta_btn_style":["field_62986b9c7c2ee"],"_ame_cpe_post_policy":["{\"accessProtection\":{\"active\":\"replace\"}}"],"popup_box_id":["popup-1"],"_popup_box_id":["field_62b1ab70ff7f5"],"_yoast_indexnow_last_ping":["1753987250"],"_dp_original":["12975"],"_edit_lock":["1754329387:7"],"_edit_last":["7"],"_thumbnail_id":["13226"]},"_links":{"self":[{"href":"https:\/\/clario.com\/wp-json\/wp\/v2\/therapeutic-areas\/13220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clario.com\/wp-json\/wp\/v2\/therapeutic-areas"}],"about":[{"href":"https:\/\/clario.com\/wp-json\/wp\/v2\/types\/therapeutic-areas"}],"up":[{"embeddable":true,"href":"https:\/\/clario.com\/wp-json\/wp\/v2\/therapeutic-areas\/5024"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/clario.com\/wp-json\/wp\/v2\/media\/13226"}],"wp:attachment":[{"href":"https:\/\/clario.com\/wp-json\/wp\/v2\/media?parent=13220"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clario.com\/wp-json\/wp\/v2\/tags?post=13220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}