{"id":12952,"date":"2025-02-08T10:28:56","date_gmt":"2025-02-08T15:28:56","guid":{"rendered":"https:\/\/clariowebstg.wpengine.com\/?post_type=articles&p=12952"},"modified":"2025-09-29T13:37:59","modified_gmt":"2025-09-29T17:37:59","slug":"researcher-spotlight-brice-cleland","status":"publish","type":"articles","link":"https:\/\/clario.com\/resources\/articles\/researcher-spotlight-brice-cleland\/","title":{"rendered":"Researcher spotlight: Brice Cleland"},"content":{"rendered":"\n

Precision Motion<\/h2>\n\n\n\n

May 27, 2025<\/p>\n\n\n

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\n \"Brice\n <\/div>\n
\n \"Brice\n <\/div>\n <\/div>\n <\/div>\n<\/div>\n\n\t\t<\/div>\n\t<\/div>\n\n<\/div>\n\n\n
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Brice Cleland, Ph.D.<\/h4>\n\n\n\n

Research Assistant Professor
Department of Physical Therapy
University of Illinois Chicago<\/p>\n\n\t<\/div>\n\n<\/div>\n\n\t<\/div>\n\n\n\n

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Opal V2R\u00ae technology has been used by thousands of researchers worldwide, and together, these researchers have published more than 750 peer reviewed papers, greatly contributing to the available body of evidence in human movement.<\/p>\n\n\n\n

APDM is a part of Clario, a leading provider of endpoint data solutions to the clinical trials industry. For more than 50 years, Clario has delivered deep scientific expertise and broad endpoint technologies to help transform lives around the world.<\/p>\n\n\n\n

The Opal V2R\u00ae solution has been utilized to assess human movement across more than 30 therapeutic indications providing richer insights and meaningful outcomes. Unlock the full potential of your research with Opal V2R\u00ae technology.<\/p>\n\n\n\n

For more information, visit our Wearable Biosensors for Research page<\/a>. <\/p>\n\n\t<\/div>\n\n<\/div>\n\n <\/div>\n<\/div>\n\n\n

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Q:<\/mark> <\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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Would you please introduce yourself, your academic background and your research interests?<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n
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A: <\/mark><\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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My name is Brice Cleland, PhD, and I am a Research Assistant Professor in the Department of Physical Therapy at the University of Illinois Chicago. My training is in Physiology\/Rehabilitation Science from Marquette University (BS, PhD) and the University of Colorado Boulder. My research investigates the mechanisms of walking recovery after neurological injury (with a focus on stroke and multiple sclerosis) and how to harness these processes to improve gait rehabilitation. To improve rehabilitation, it\u2019s imperative to understand the physiological processes underlying walking recovery and how to enhance these processes. To address these questions, my research uses a multi-faceted approach with tools such as magnetic resonance imaging, transcranial magnetic stimulation, transcranial direct current stimulation, peripheral stimulation, electromyography, and behavioral and biomechanical measures.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n <\/div>\n<\/div>\n\n\n

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Q:<\/mark> <\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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Do you have a personal story that led to your interest in human movement\/ neurodegenerative disease research? What continues to drive your ambitions as a scientist?<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n
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A: <\/mark><\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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My interest in human movement began in high school in an interest in the physiology of running. I read books such as \u201cThe Lore of Running\u201d by Timothy Noakes, and \u201cExercise Physiology: Human Bioenergetics and Its Applications\u201d by George Brooks. Because of my interest, I got involved in human subjects research as an undergraduate student, working in a research lab working with people with multiple sclerosis. I discovered that there was much work to be done to advance rehabilitation for individuals with neurological injury. My personal connections with participants continues to drive my interests in working to continue improving recovery for these individuals.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n <\/div>\n<\/div>\n\n\n

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Q:<\/mark> <\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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How has Clario\u2019s APDM Opal V2R\u00ae System been most useful in your research endeavors?<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n
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A: <\/mark><\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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The Clario\u2019s APDM Opal V2R\u00ae System is an excellent tool for evaluating walking spatiotemporal kinematics. Previously, these types of measurements could only be performed using instrumented treadmills or instrumented walkways. These have cost and space limitations that Clario\u2019s APDM Opal V2R\u00ae System circumvents. Measurements can be made in a variety of free-living and laboratory environments at a relatively low cost.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n <\/div>\n<\/div>\n\n\n

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Q:<\/mark> <\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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What research projects or questions are you currently working on?<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n
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A: <\/mark><\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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Currently, I am working on an NIH R21 that is investigating which motor pathways may compensate for impairment after stroke, including pathways from the non-lesioned hemisphere such as the corticoreticulospinal tract (CREST) and spinal pathways. In this project, we are using fMRI and TMS to provide insight into the CREST and lower limb functional tests including walking speed, spatiotemporal kinematics, and ankle movement to determine how these compensatory motor pathways impact lower limb function. I am also working on a pilot project which compares effects of moderate and high intensity treadmill training on symptomatic fatigue and walking in people with MS with elevated fatigue and walking dysfunction.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n <\/div>\n<\/div>\n\n\n

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Q:<\/mark> <\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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Where do you see the use of wearable IMU\u2019s in human movement research going in the next 5 years?<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n
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A: <\/mark><\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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In the next 5 years, I think wearable IMU\u2019s will continue to expand in their ability to be used in free-living conditions for extended durations. I also expect that the accuracy the predictive models used by these will continue to improve, particularly with the burgeoning interest in machine learning and AI.<\/p>\n\n\t<\/div>\n\n<\/div>\n\n <\/div>\n<\/div>\n\n\n

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Q:<\/mark> <\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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Fill in the blank:<\/strong><\/mark> When I\u2019m not working on a research project, you can find me\u2026<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n
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A: <\/mark><\/strong><\/h2>\n\n\t<\/div>\n\n\n\n
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…out running around Chicagoland or playing with my kids (aged 3 and 6).<\/p>\n\n\t<\/div>\n\n<\/div>\n\n <\/div>\n<\/div>\n\n\n

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Check out some of this researcher’s recent publications<\/h2>\n\n\t<\/div>\n\n<\/div>\n\n\n
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\n Peer-Reviewed<\/span>

The Relation Between Hemiparetic Gait Patterns and Walking Function After Stroke, as Measured with Wearable Sensors<\/h3>Read<\/span><\/a> <\/article>\n <\/div>\n\n\t<\/div>\n\n<\/div>\n\n <\/div>\n<\/div>\n\n\n
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